The Journal of nervous and mental disease . ngexamination seem to point directly to an affection of themuscles themselves, and indicate the necessity of theircareful microscopical examination. Others, also reasoningin same manner, have examined pieces of muscles frommyotonia congenita, Ponfick, Petrone, Jacusiel-Grawitz,Knud Pontoppidan, Rieder, and finally Erb, but all ofthem, with the exception of Erb, with purely negative re-sults. Erbs microscopical examination of three cases re- THOMSENS DISEASE. 141 vealed so much that was new that the results in my case,which differ so little clinically
The Journal of nervous and mental disease . ngexamination seem to point directly to an affection of themuscles themselves, and indicate the necessity of theircareful microscopical examination. Others, also reasoningin same manner, have examined pieces of muscles frommyotonia congenita, Ponfick, Petrone, Jacusiel-Grawitz,Knud Pontoppidan, Rieder, and finally Erb, but all ofthem, with the exception of Erb, with purely negative re-sults. Erbs microscopical examination of three cases re- THOMSENS DISEASE. 141 vealed so much that was new that the results in my case,which differ so little clinically from those of Erb, wereawaited with considerable interest. I may say right hereat the outset that all the points seen by Erb were substan-tially corroborated by my examination, but still more wasseen, and this seems to me, as will be shown, to be of par-ticular importance for the explanation of many of the phe-nomena seen clinically. The specimens were obtained from a piece of the qua-driceps femoris muscle, which was removed from the pa-. Fig. 1.—Normal muscle. Quadriceps femoris. Transverse section. X 300. tient under antiseptic precautions, and with the use of anEsmarch bandage. The fresh piece of muscle was droppedimmediately after excision into a one-half-per-cent solutionof chromic acid and left there until sufficiently was then transferred into strong alcohol, imbedded incelloidin and cut both transversely and sections thus obtained were then stained, some ofthem in an ammoniacal solution of carmine, and others ina one-half-per-cent solution of chloride of gold. There-upon the specimens were mounted in glycerin. It is wellhere to lay stress upon this fact, as the illustrations in Erbs 142 GEORGE \V. JACOB Y. monograph, repeatedly referred to above, were taken fromspecimens mounted in Canada balsam, and to this circum-stance I am inclined to attribute the lack of details whichis apparent in those drawings, and which differs so mark-edly f
Size: 1939px × 1289px
Photo credit: © The Reading Room / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookcentury1800, bookdecade1870, booksubjectpsychologypathologic
