. On modern methods of treating fractures . e ossification of the callus granulations. Delayed unionor non-union may be caused by interference with any one ofthese factors. Interference with the Laying Down of GranulationTissue or Pro-Callus.—The granulation tissue which is the pre-cursor of callus is laid down by the open ends of the vascular ■266 MODERN METHODS OF TREATING FRACTURES canals of the bone, and to some extent also by the deep layerol the periostenm where it is torn from the bone. Ent theperiosteinn acts rather as a limitinf:^ membrane than as amatrix of new bone. If it is left ti
. On modern methods of treating fractures . e ossification of the callus granulations. Delayed unionor non-union may be caused by interference with any one ofthese factors. Interference with the Laying Down of GranulationTissue or Pro-Callus.—The granulation tissue which is the pre-cursor of callus is laid down by the open ends of the vascular ■266 MODERN METHODS OF TREATING FRACTURES canals of the bone, and to some extent also by the deep layerol the periostenm where it is torn from the bone. Ent theperiosteinn acts rather as a limitinf:^ membrane than as amatrix of new bone. If it is left tightly adherent to the bone,then at that snrface no pro-calhis granulations appear. Simi-larly, a fringe of periosteum lapping over the end of the bone willinhibit at that point the formation of callus. This is shown in the accompanying diagram {Fig. 130). In Athe bone has been broken and the periosteum completely tornthrough, remaining attached to each fragment. No callus granu-lation can occur except at the ends of the bone, which are.
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