The pathology and surgical treatment of tumors . substance containing few fibres and occa-sional wandering cells. During the devel-opment of myxomatous into connectivetissue the fibrous tissue in the meshesbecomes more abundant, while the intercellular substance is diminishedin quantity. If a group of cells should become arrested in their devel-opment at an early stage and be set aside, it is to be expected thattissue-proliferation from them would result in a connective-tissue tumorof lowly-organized tissue—a myxoma. On the contrary, arrest ofdevelopment at a later stage would result in a tumo
The pathology and surgical treatment of tumors . substance containing few fibres and occa-sional wandering cells. During the devel-opment of myxomatous into connectivetissue the fibrous tissue in the meshesbecomes more abundant, while the intercellular substance is diminishedin quantity. If a group of cells should become arrested in their devel-opment at an early stage and be set aside, it is to be expected thattissue-proliferation from them would result in a connective-tissue tumorof lowly-organized tissue—a myxoma. On the contrary, arrest ofdevelopment at a later stage would result in a tumor-matrix which wouldproduce a connective-tissue tumor of a higher type—a fibroma. Thestage at which development of the mucous cells in the embryo is arresteddetermines whether the tumor from such a matrix is to be a myxoma ora fibroma. The intrinsic capacity of mature connective tissue to revert toits original embryonic state accounts for the frequency tvith zvhicJi thestroma of all tumors undergoes myxomatous degeneration. A post-natal 408. Fig. 286.—Connective-tissue cells fromyoung umbilical cord: processes of cellsunite to form protoplasmic network;fibrous elements slightly developed (afterPiersol;. MYXOMA. 409 matrix of myxoma is created if the pre-existing connective-tissue cellsrevert to their original embryonic state and remain unspecialized. Histolog-y.—The histological structure of a myxoma is subject tomany variations. The variable structure depends on the amount andcharacter of the intercellular gelatinous substance and the abundanceand vascularity of its stroma. Mucin is a substance which in the livingbody is rapidly destroyed and eliminated. In a myxoma the retentionof this substance gives rise to hydropic conditions, and this reten-tion occurs in myxomatous tumors if the production and absorption ofmucin are arrested. Myxoma may occur as a clear, colorless, gelatinous mass whichdiffers from fluid only in its greater consistence. The delicate stromaof such
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectneoplas, bookyear1895
