. Endocrinology. ls and the large groupsof Leydig cells (most often in between these) typical eosinophilecells, so numerous and constant that the phenomenon could notbe caused by chance. Although at present I cannot explain thispeculiar phenomenon, I am inclined to think that these cellspossibly represent a passing (transient) stage during a trans- 28b ENDOCRINOLOGY OF SEXUAL GLANDS formation of connective tissue cells to Leydig cells, especially inthe case where these are greatly augmented. ///. Experiments throwing light upon female sexual Transplantations I performed a cons
. Endocrinology. ls and the large groupsof Leydig cells (most often in between these) typical eosinophilecells, so numerous and constant that the phenomenon could notbe caused by chance. Although at present I cannot explain thispeculiar phenomenon, I am inclined to think that these cellspossibly represent a passing (transient) stage during a trans- 28b ENDOCRINOLOGY OF SEXUAL GLANDS formation of connective tissue cells to Leydig cells, especially inthe case where these are greatly augmented. ///. Experiments throwing light upon female sexual Transplantations I performed a considerable number (167) of these in 1914-17, arranging them under the above-mentioned groups, whichcontain all possible types. All of the experiments co^rroboratedthe theories of the endocrine function of the ovaries with regardto the sexual characters, in auto- as well as in iso-transplanta-tions. By heterological isotransplantations I verified Steiuachsfeminization experiments. An ovary transplanting from a posi-. Fig. 13Guinea-pig No. .37. Positivp heteroiogical transplantation of tlie ovary(feminization). Microphotograph. In the transplant are found follicles andtheca lutein tissue, but no corpora lutea. tive feminization in a guinea-pig can be seen iii Fig. 13, whichshows how nicely a transplanted ovary can preserve itself in thecastrated male organism. In all the series of ovary transplantations altogether 167transplants were used. As opposed to earlier scientists I exam-ined these in serial sections, in order to substantiate the appear-ance of the three elements (follicles, theca lutein tissue and cor-pora lutea), and thereby be able to determine the question ofthe place of production of the female sexual hormones. Resume of the results of ovary transplantation: SAND 289 The place of transplantation and the consanguinity of thedonor and the host seemed to be factors of slight importance forthe result. Autotransplantations were successful, on guinea-pigs espe-cially, easier
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