RNA INTERFERENCE
Interfering RNA (RNAi). Interfering RNA is a mean for the cell to destroy the RNA parasites (viruses RNA, transposons). In the cytoplasm, a proteic complex (named RISC for RNA-induced silencing complex), associated to a fragment of RNA (RNA guide), links to the molecule of the virus RNA or transposon. The latter is then cut by the endonuclease activity of RISC (cleavage) then destroyed. The cell then eliminates all foreign RNA. RNA interference is currently under study to turn off individual gene expression (silencing) in the framework of the development of new therapies. See. images 1072907, 1073007, 1073107, 1073207, 1073307 and 1073407 for the detailed explanation of the RNA interference.
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