. A manual of poisonous plants, chiefly of eastern North America, with brief notes on economic and medicinal plants, and numerous illustrations. Poisonous plants. SCHIZOPHYTA—SCHIZOMYCETRS 173 isease. The organism itself may or may not gain entrance into the circula- on or organs. Immunity. .A^s before stated, anti-toxins are not developed. Agglutinins, Dwever, are developed. Bacillus typhosus, Zopf Disease produced. Typhoid fever. Animals infected. Man. Inoculation of experimental animals usually sgative, except when injected in considerable Fig. 29. Typhoid fever bacillus. (Baci
. A manual of poisonous plants, chiefly of eastern North America, with brief notes on economic and medicinal plants, and numerous illustrations. Poisonous plants. SCHIZOPHYTA—SCHIZOMYCETRS 173 isease. The organism itself may or may not gain entrance into the circula- on or organs. Immunity. .A^s before stated, anti-toxins are not developed. Agglutinins, Dwever, are developed. Bacillus typhosus, Zopf Disease produced. Typhoid fever. Animals infected. Man. Inoculation of experimental animals usually sgative, except when injected in considerable Fig. 29. Typhoid fever bacillus. (Bacillus typhosus). Section from spleen showing bacteria clustered in center. After Flugge. Pathogenesis. The organism invades the solitary lymph nodes and Peyer's itches in the intestine and produces more or less necrosis and sloughing of 5sue. By means of the lymphatic channels, the internal organs are all infected, irticularly the spleen which becomes very much enlarged. The bacilli invade le blood, and hence the disease is a true bacteremia. When they lodge in bony 5sues, osteitis, periosteitis, and osteomyelitis may be produced. Poisonous properties. No soluble toxin has been discovered, an endotoxin, )wever, is present and may be secured through self digestion in cultures, or by inding and extracting the bodies of the bacteria. Immunity. No true anti-toxin serum has been produced, inasmuch as no xin has been discovered. The blood serum of typhoid patients agglutinates e bacteria. Vaccination with killed cultures produces an immunity which lasts obably in most cases several years. The blood serum of animals immunizes [ainst typhoid bacilli, but is not used because it is quickly throvim out of the stem when injected, and because it possesses very little curative Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the or
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