Gynecology . s unique color. There has been somequestion as to the origin of the cells that make up the yellow membrane, but itis now generally accepted that they represent the hypertrophied epithelialcells of the membrana granulosa. They are large and polymorphous, with alarge nucleus, and resemble somewhat decidual cells. The cell-body containsdrops of fat and yellow pigment granules that give the characteristic color. PHYSIOLOGY OF THE UTERUS AND OVARIES 39 These are the so-called lutein cells. Into this lutein layer sprout blood-vesselsand connective-tissue radial projections, which vascul
Gynecology . s unique color. There has been somequestion as to the origin of the cells that make up the yellow membrane, but itis now generally accepted that they represent the hypertrophied epithelialcells of the membrana granulosa. They are large and polymorphous, with alarge nucleus, and resemble somewhat decidual cells. The cell-body containsdrops of fat and yellow pigment granules that give the characteristic color. PHYSIOLOGY OF THE UTERUS AND OVARIES 39 These are the so-called lutein cells. Into this lutein layer sprout blood-vesselsand connective-tissue radial projections, which vascularize and support thecorpus luteum. The resultant picture of large epithelial cells, with pale stain-ing nuclei lying in contact with small thin-walled blood-vessels, corresponds tothe structural appearance commonly regarded as characteristic of organs ofinternal secretion. As will be seen, this is one of the arguments for the beliefthat the seat of the internal secretion of the ovary is in the corpus Fig. 16.—Graafian Follicle as it Appears in the Surrounding Ovarian below the follicle is a corpus albicans. After the corpus luteum reaches the height of its development it graduallyshrinks. The yellow coloring matter is absorbed and the lutein cells degen-erate in hyalin masses, held together by strands of connective tissue. Thehyalin colorless masses then roll together in cloud-like convolutions and formthe corpus albicans. This process of regression occupies about four corpus albicans may remain a long time, but the hyalin material is event-ually entirely absorbed and all trace of the former corpus luteum disappears,excepting the scarred indentation on the surface of the ovary. The size of the corpus luteum varies considerably, reaching sometimes even 40 GYNECOLOGY in non-pregnant women a diameter of 2 cm. If pregnancy occurs its develop-ment is more pronounced, reaching its height about the second month. Fromthe third month its regression is v
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