. Physical diagnosis . orpuscles around. If this brownish orpurplish tint occurs in all the corpuscles, it has no pathological sig-nificance, but merely means that the staining has been incorrectlyperformed. (c) Stippling refers to fine, dark-blue dots scattered over thepink surface of a red corpuscle, as if a charge of fine shot had beenfired into it. All the abnormalities just described are to be found in any of the types of severe anaemia,whether primary or secondary,but stippling may also be foundwithout anwmia in some casesof lead poisoning, and is there-fore useful as a confirmatorysign
. Physical diagnosis . orpuscles around. If this brownish orpurplish tint occurs in all the corpuscles, it has no pathological sig-nificance, but merely means that the staining has been incorrectlyperformed. (c) Stippling refers to fine, dark-blue dots scattered over thepink surface of a red corpuscle, as if a charge of fine shot had beenfired into it. All the abnormalities just described are to be found in any of the types of severe anaemia,whether primary or secondary,but stippling may also be foundwithout anwmia in some casesof lead poisoning, and is there-fore useful as a confirmatorysign in cases of this disease. Nucleated red corpuscles aredivided into two main varieties :(1) normoblasts, which are ofthe size of normal corpuscles;and (2) megaloblasts, which arelarger than normal corpuscles(see Fig. 212). The nucleusof the normoblast is generallysmall and deeply stained, navyblue. In the megaloblast the nucleus may have the same charac-teristics or may be much larger and paler, with a distinct intranu-. Fig. 212.—Nucleated Red Cells, m, m, Megalo-blasts ; n, normoblast; s, stippled cell. THE BLOOD. 471 clear network. The protoplasm of both varieties is often discol-ored, murky, gray, or even blue, and sometimes stippled, so thatby beginners the cell may be mistaken for a leucocyte. The mis-take may be avoided, however, after some experience. In the pro-toplasm of nucleated cellsthere are often concentricrings like the layers in anoyster shell, and their outlineis usually more irregular thanthat of any leucoctye. Fur-ther points of differentiationmust be learned by practice. 2. —In normalblood four main varieties maybe distinguished: (a) Polynuclears or poly-morphonuclear neutrophiles. (6) Lymphocytes (largeand small). (c) Eosinophiles. (d) Mast cells.(a) Polynuclears. ■— The deeply stained, markedly con-torted nucleus assumes a greatvariety of shapes in differentcells, and is surrounded by apinkish protoplasm studdedwith spots or granules ju
Size: 1573px × 1589px
Photo credit: © Reading Room 2020 / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookcentury1900, bookdecade1900, bookpublis, booksubjectdiagnosis
