. A manual of diseases of the nervous system. tion must be re-lateral and posterior sclerosis. A, upper J, T J. J- i: j-i,„dorsal; B, last dorsal; C, mid-lumbar. furred to the disease ot the pos-The posterior columns are free from terior columns, which, greatestsclerosis in C, except in their anteriorparts; in B the disease involves the middle and anterior parts of both and columns except in theneighbourhood of the neck of the horn ; in A the sclerosis is slighter and is con-fined to the middle three fifths of these columns. The sclerosis of the lateralcolumns in C i
. A manual of diseases of the nervous system. tion must be re-lateral and posterior sclerosis. A, upper J, T J. J- i: j-i,„dorsal; B, last dorsal; C, mid-lumbar. furred to the disease ot the pos-The posterior columns are free from terior columns, which, greatestsclerosis in C, except in their anteriorparts; in B the disease involves the middle and anterior parts of both and columns except in theneighbourhood of the neck of the horn ; in A the sclerosis is slighter and is con-fined to the middle three fifths of these columns. The sclerosis of the lateralcolumns in C is limited, on the right, to the pyramidal tract, on the left it extendsin front of this; in B it is very dense in the whole lateral column, involving notonly the pyramidal tract but the limiting layer, and part of the mixed zone; inA it is similar in extent but slighter in degree. There is some increase of tissuethroughout the anterior columns, and a focus of sclerosis near the anterior fissure,on the right in A and B, on both sides in • Oppenheim, «Neur. Cent., 1888, p. 647. t I am indebted to Mr. J. Hopkins for the opportunity of drawing these patient was a man aged twenty-one, in whom weakness of the legs commenced ATAXIC PARAPLEGIA. 509 in tlie dorsal region, involves there the fibres that conduct impulsesfrom the muscles, probably to the cerebellum.* The effect must beto lessen the cerebellar guidance, and this explains the resemblanceof the inco-ordination to that in cerebellar disease. The fact thatthe disease does not extend into the lumbar root-zone accounts forthe integrity of the muscle-reflex action, and enables us to understandthis marked difference from tabes. Disease of the direct cerebellartract probably has an influence similar to that, of the posteriormedian columns. That interruption of the conducting path inthe cord will produce inco-ordination is, as we have seen (p. 258),well established. The sclerosis in ataxic paraplegia occupies a
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