. A manual of diseases of the nervous system. polio-myelitis as merely accidental complications. Pathological Anatomy.—It is rare at the time of death for anymuscles to be actually larger than natural. Sometimes, however, theyare enlarged, and the fibres themselves have been found hypertrophied,just as they have been in excised parts. There has also been founda great increase in the nuclei, atrophy of the fibres, vacuolation,and division of fibres. Most of those that are affected are belowthe normal size. They are pale and yellowish in colour, and often, tothe naked eye, resemble perfectly mas
. A manual of diseases of the nervous system. polio-myelitis as merely accidental complications. Pathological Anatomy.—It is rare at the time of death for anymuscles to be actually larger than natural. Sometimes, however, theyare enlarged, and the fibres themselves have been found hypertrophied,just as they have been in excised parts. There has also been founda great increase in the nuclei, atrophy of the fibres, vacuolation,and division of fibres. Most of those that are affected are belowthe normal size. They are pale and yellowish in colour, and often, tothe naked eye, resemble perfectly masses of adipose tissue. Theresemblance is not merely one of aspect. As seen under the micro-scope, it may be difficult for the observer to realise that he is notlooking at a fatty tumour. Nothing may be at first visible but fat-cells, precisely like those of adipose tissue. Among the cells, however,are tracts of nucleated fibrous tissue, and a closer examination of theseshows that the tracts contain also muscular fibres (Fig. 165), most of. Fl9. 166.—GastrocneTnins muscle; muscular fibres, irregularly nar-rowed and in part degenerated, lie among tracts of nucleated fibroustissue, separated by adipose tissue. them much narrower than normal. They are also irregular in width;a broad fibre, for instance (as in the figure), suddenly becomingnarrow. The fibres for the most part preserve their transverse striation, butwhere they are narrowest this may have in part disappeared, either bygranular degeneration, or, more commonly, by a simple fading of thestrisB. In the narrowed fibres the strise are sometimes farther apartthan normal. In other parts broad fibres may be seen, normal or VOL. I. 37 578 SPINAL COED. nearly normal in aspect (Fig. 166), coursing among tlie fat-cells, andaccompanied by a smaller amount of fibrous tissue. Fibres occasion-ally present fatty degeneration, a longitudinal striation or fissuring,vitreous (waxy) degeneration, or vacuolation, but tliese are
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