Diseases of metabolism and of Diseases of metabolism and of the blood, animal parasites, toxicology diseasesofmetabo00cabo Year: 1906 BACTERIOLOGICAL EXAMINATION* 291 number of diseases in which, particularly in especially severe cases, the pathogenic agents enter the blood. Formerly we contented ourselves with a microscopic investigation of fresh r stained blood to determine the presence of bacteria. Bui this process should only be resorted to for the determination of tbe spirilli of relapsing fever, or, perhaps, of the bacilli of anthrax. In other case- it may lead to errors, first because
Diseases of metabolism and of Diseases of metabolism and of the blood, animal parasites, toxicology diseasesofmetabo00cabo Year: 1906 BACTERIOLOGICAL EXAMINATION* 291 number of diseases in which, particularly in especially severe cases, the pathogenic agents enter the blood. Formerly we contented ourselves with a microscopic investigation of fresh r stained blood to determine the presence of bacteria. Bui this process should only be resorted to for the determination of tbe spirilli of relapsing fever, or, perhaps, of the bacilli of anthrax. In other case- it may lead to errors, first because of the small number of germs that may be present, ami. secondly, because confusion with accidental bacterial contaminations may readily occur. It is therefore advisable to puncture a vein of the arm under -trict antiseptic precautions, to withdraw 1 to 2 of blood, and to prepare culture-, besl in bouillon, or to determine by animal experiments the probable presence of pathogenic bacteria. In this manner we are able to determine with certainty in the circulating blood the presence of streptococci, staphylococci, pneumococci, the bacilli of enteric fever, of the plague, of tuberculosis and others. [Typhoid bacilli have repeatedly been cultivated from the blood of doubtful febrile cases before the Widal reaction bad appeared. Eence this procedure may be of great value in obscure cases. Tbe same is true of the cultivation of pneumo- cocci from the blood in obscure pneumococcus infection- and ••central pneu- '— Ed. I The determination of the pathogenic agents just mentioned can only be gnated as an auxiliary factor in diagnosis, but the recognition of spirilli in the blood i- the only mean- for a positive diagno- of relapsing fever. As a rule ibis determina- tion i- very easy, for the peculiar curved form of the spirilli (see Fig. 17) precludes confusion with other organisms. Their Dumber is usually very large; our detection of them is greatly facilitated by thei
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