. The elements of pathological histology with special reference to practical methods . are also found. Sarcomata never behave inan indifferent manner to their surroundings, as do the benign tumours;the adjoining connective tissue is always in a state of cellular in-filtration, so that no sharp line of demarcation can be drawnmicroscopically, even when such appears to the naked eye to metastatic dissemination of sarcomata usually takes place by wayof the blood-vessels. The following varieties of sarcoma may be distinguished:— 12. (i.) The Round-Celled Sarcoma.—This consists of round c
. The elements of pathological histology with special reference to practical methods . are also found. Sarcomata never behave inan indifferent manner to their surroundings, as do the benign tumours;the adjoining connective tissue is always in a state of cellular in-filtration, so that no sharp line of demarcation can be drawnmicroscopically, even when such appears to the naked eye to metastatic dissemination of sarcomata usually takes place by wayof the blood-vessels. The following varieties of sarcoma may be distinguished:— 12. (i.) The Round-Celled Sarcoma.—This consists of round cellswith very little interstitial substance, and has its representative in theyoungest stage of granulation tissue. The cells are commonly small,about the size of leucocytes (Fig. 39, a), have a very scanty amountof protoplasm and a relatively large round or oval vesicular nucleus.(Owing to the sliglit development and fragifaty of the body of thecell, often nothing is seen but naked nuclei ^hen fresh pieces of atumour of this kind are torn up.) The inteiSellular substance is so. Fif!. Laroe Round-Celled Sarcoma of the Ribs, x 545.(Stained with alum cochineal.) a, Reticulum; 6, Stellate cells of reticulum;c, Sarcoma cells, round, or flattened where they come in contact. scanty that pencilHng or shaking is often necessary before it becomesvisible, and it is formless, finely fibrous, or reticulated (Fig. 31, a). 88 TUMOURS OR NEW-FORMATIONS When the reticulum resembles the supporting substance of lymphaticglands, which often happens in round-celled sarcomata of such glandsand of the adenoid tissue of mucous membranes, we may also speakof a lymplio-sarcoma. In some round-celled sarcomata the cells are perceptibly largerthan leucocytes, and their nuclei strikingly large and vesicular. Insuch a case the sarcoma may be described as a large round-celledsarcoma (Fig. 31). The round-celled sarcomata are very soft and juicyowing to their richness in cells, and are like
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectpatholo, bookyear1895
