Scientific and applied pharmacognosy intended for the use of students in pharmacy, as a hand book for pharmacists, and as a reference book for food and drug analysts and pharmacologists . ckness of wall mm. The outline of the lumina of the cells variesfrom nearly smooth to slightly irregularly undulate or more or less raggedand angular.—After Stingel, Amer. Jour. Pharm., 1913, p. 391. about per cent, and forms prisms (Fig. 96), which are not col-ored by concentrated sulphuric or nitric acid. An aqueous solution ACONITE 217 of the alkaloid, after acidulating with acetic acid, gives o
Scientific and applied pharmacognosy intended for the use of students in pharmacy, as a hand book for pharmacists, and as a reference book for food and drug analysts and pharmacologists . ckness of wall mm. The outline of the lumina of the cells variesfrom nearly smooth to slightly irregularly undulate or more or less raggedand angular.—After Stingel, Amer. Jour. Pharm., 1913, p. 391. about per cent, and forms prisms (Fig. 96), which are not col-ored by concentrated sulphuric or nitric acid. An aqueous solution ACONITE 217 of the alkaloid, after acidulating with acetic acid, gives on theaddition of a solution of potassium permanganate a red crystallineprecipitate. Aconitine decomposes quite readily and several of itsderivatives have been isolated: benzaconine, an inert alkaloid andaconine which produces apparently contrary physiological effectsto aconitine. The alkaloid napelline may be isomeric with also contains considerable aconitic acid, which is chieflycombined with calcium and occurs in other genera of the , viz.: Delphinium and Adonis; besides considerablestarch; a little mannitol and a resin. The other alkaloids are. Fig. 96.—Aconitine: orthorhombic crystals, crystallized from alcoholic solutions. amorphous and non-toxic, and of these isaconitine (napelline) hasbeen employed medicinally. Aconitine (acetyl-benzoyl-aconine) occurs in colorless, nearlytransparent, glistening crystals. From alcoholic solution ortho-rhombic prisms (Fig. 96) usually predominate while from solutionsin which chloroform is the solvent, the tendency is for small isolatedrosette aggregates to separate. The crystals vary in length mm. to 1 mm., although crystals as large as 1 cm. in length cm. in thickness have been obtained. Upon rapidly heating, theM. P. is 197°-198° C. At 25° C. one part of aconitine is soluble in3226 parts of water; 22 parts of alcohol; 44 parts of ether; and of benzene. The gold salt of acon
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