The Medical clinics of North America . -sion. Palpebral apertures markedlywidened as compared with Fig. 74. r^ *^^v l ?^>: Fig. 76.—Case I. Three weekslater. Note further reduction in puf-finess of face and neck. Also notebeginning of hair growth, which is ofa fine texture. Eyes still brighter. Fig. 77.—Case I. February,1922, four months after beginningthyroxin therapy. Note the heavygrowth of hair. Facial expressionmore vouthful and cheerful. 336 HANS LISSER longer constipated. He has thrown off most of his extra cover-ings at night and no longer feels the cold. In fact, this increasedwarm


The Medical clinics of North America . -sion. Palpebral apertures markedlywidened as compared with Fig. 74. r^ *^^v l ?^>: Fig. 76.—Case I. Three weekslater. Note further reduction in puf-finess of face and neck. Also notebeginning of hair growth, which is ofa fine texture. Eyes still brighter. Fig. 77.—Case I. February,1922, four months after beginningthyroxin therapy. Note the heavygrowth of hair. Facial expressionmore vouthful and cheerful. 336 HANS LISSER longer constipated. He has thrown off most of his extra cover-ings at night and no longer feels the cold. In fact, this increasedwarmth of the body and the realization of it was the first changenoted by the patient after thyroxin was begun. It seems diffi-cult to believe and embarrassing to record that this patientwent the rounds of physicians for over ten years in quest ofdiagnosis and relief, and it is because of this that his case hasbeen herewith recorded. Myxedema is not a common disease,but it should not be relegated to the category of medical rareties,. Fig. 78.—Case I. August, 1922, nine months after beginning heavy growth of hair and compare with Fig. 70. One notes a similarityagain to picture taken seventeen years ago. and our experience with that of others recently published leadsone to believe that there are many such patients in our com-munities unrecognized and unnecessarily afflicted. A Case of Childhood Myxedema. In Endocrinology, March,1922, vol. 6, pp. 2?r>. Murray B. Gordon presents a studyof 280 cases of childhood myxedema that have been reportedin North America. Sixty cases had previously been collectedand published by < teler. The locations of the 280 rases reported ADULT AND CHILDHOOD MYXEDEMA 337


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