. The Biochemistry of B vitamins. Vitamins; Vitamin B complex. 314 THE BIOCHEMISTRY OF B VITAMINS Because of the nicety of quantitative response obtainable, Sarma and co-workers have employed Corcyra as an assay animal for thiamine, riboflavin, and pyridoxine, and obtained results which agree well with those obtained by other methods. Strain differences, however, are suf- ficiently great that "pure" strains would be desirable for routine insect assay 36. Figure 4. Growth of Corcyra Cephnlonicn St. larvae with various amounts of biotin concentrate added to an egg-white die
. The Biochemistry of B vitamins. Vitamins; Vitamin B complex. 314 THE BIOCHEMISTRY OF B VITAMINS Because of the nicety of quantitative response obtainable, Sarma and co-workers have employed Corcyra as an assay animal for thiamine, riboflavin, and pyridoxine, and obtained results which agree well with those obtained by other methods. Strain differences, however, are suf- ficiently great that "pure" strains would be desirable for routine insect assay 36. Figure 4. Growth of Corcyra Cephnlonicn St. larvae with various amounts of biotin concentrate added to an egg-white diet. Ten larvae per test group. Of even greater interest, however, is the work done by this group on vitamin metabolism in In a manner entirely analogous to that of higher animals, thiamine-deficient Corcyra larvae show fatty tissue and nerve degeneration, and the pyruvic acid content of the deficient larvae increases to eight times that of the normal animals (p. 403), and decreases again on a high thiamine diet. Again, vitamin B6 deficient larvae on high tryptophan diets excrete a yellow pigment which disappears on supplementation of the diet with pyridoxine, in a manner remarkably suggestive of the abnormal xanthurenic acid (yellow) excretion in vita- min B6 deficient mammals (p. 428). As in mammals, tryptophan alone. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Williams, Roger John, 1893-. New York : Reinhold Pub. Corp.
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