. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 454 G. M. HOLMAN AND B. J. COOK From our earlier experiments, the site of action for the excitatory peptide seemed to be the visceral muscles of the hindgut. However, there was the pos- sibility of a localized neural network which, if sensititive to the peptide, might indirectly stimulate the muscle fibers. This possibility was eliminated by treating an innervated hindgut with tetrodotoxin (10~6 g/ml). Four minutes after treat- ment, all neural function was abolished. At this time, the excitatory peptide was added to the mus
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 454 G. M. HOLMAN AND B. J. COOK From our earlier experiments, the site of action for the excitatory peptide seemed to be the visceral muscles of the hindgut. However, there was the pos- sibility of a localized neural network which, if sensititive to the peptide, might indirectly stimulate the muscle fibers. This possibility was eliminated by treating an innervated hindgut with tetrodotoxin (10~6 g/ml). Four minutes after treat- ment, all neural function was abolished. At this time, the excitatory peptide was added to the muscle chamber, and the hindgut responded by showing all four B. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marine Biological Laboratory (Woods Hole, Mass. ); Marine Biological Laboratory (Woods Hole, Mass. ). Annual report 1907/08-1952; Lillie, Frank Rattray, 1870-1947; Moore, Carl Richard, 1892-; Redfield, Alfred Clarence, 1890-1983. Woods Hole, Mass. : Marine Biological Laboratory
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