American journal of physiology . n. The hunger contractions conformed to the type * Carlson: this Journal, 1913, vol. , p. 369. Polyphagia in Pancreatic Diabetes 315 described as type I and there was no change during the succeedingdays (Nov. 28-30 inclusive). Figure i—An examination of theurine revealed the absence of sugar. The animal was, therefore, t^hl^ 1 inir n Dog I. Figure 2. Jan. 7, 1913. About two-thirds the original size. Characterof the stomach contractions after pancreatic diabetes was well estabhshed; type IIand III contractions superimposed on periods of marked tetany. Plai
American journal of physiology . n. The hunger contractions conformed to the type * Carlson: this Journal, 1913, vol. , p. 369. Polyphagia in Pancreatic Diabetes 315 described as type I and there was no change during the succeedingdays (Nov. 28-30 inclusive). Figure i—An examination of theurine revealed the absence of sugar. The animal was, therefore, t^hl^ 1 inir n Dog I. Figure 2. Jan. 7, 1913. About two-thirds the original size. Characterof the stomach contractions after pancreatic diabetes was well estabhshed; type IIand III contractions superimposed on periods of marked tetany. Plain horizontalline represents o mm. bromoform pressure. used for the study of another problem until the Christmas Jan. 4, 1913, it was noticed that the dog ate ravenously, butwas in an extremely emaciated condition. The skin was dry; thedog had the mange; there were multiple small wounds about thetoes and ears; and a purulent discharge issued from both urine reduced Fehlings () and fermented readily with. Dog I. Figure 3. Jan. 24, 1913. About four-sevenths the original size. Wellmarked type III contractions of the empty stomach. The horizontal line representso mm. bromoform pressure. yeast. From Jan. 6, 1913, on, daily tracings were taken from thestomach 24 hours after the last meal. On Jan. 6, 7, and 11, type III contractions predominated, super- 3i6 Arno B. Luckhardt imposed on periods of tetany lasting from i to 7 minutes (Fig. 2)-From the nth of January on, type III was the most prominenttype of contraction, with occasional reversion to type II. On thei8th, 2ist, and 24th of January the stomach was in tetany, withtype III contractions most pronounced (Fig. 3). On these daysthe dog ate a good deal of lean meat, as is seen from the followingtable: TABLE I Date1913 Body weightin kg. Food in gm. Food in gm. per kg. body weight Jan. 6 350 Jan. 7 313 Jan. 12 345 429 Jan. 15 460 Jan. 18 400 Jan.
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