A treatise on the nervous diseases of children, for physicians and students . e character of thetwitchings, and the general choreic behavior of the childhelped me to exclude petit mal and to recognize the caseas one of true chorea. The diagnosis was corroborated bythe very prompt result of antichoreic treatment. Morbid Anatomy and Pathology.—In consideringthis part of the subject we meet with very much the samedifficulties which we encountered with regard to epilepsy,and the resemblance between the two is also a close one inthis respect, that we not only have a general functional dis-ease, whi
A treatise on the nervous diseases of children, for physicians and students . e character of thetwitchings, and the general choreic behavior of the childhelped me to exclude petit mal and to recognize the caseas one of true chorea. The diagnosis was corroborated bythe very prompt result of antichoreic treatment. Morbid Anatomy and Pathology.—In consideringthis part of the subject we meet with very much the samedifficulties which we encountered with regard to epilepsy,and the resemblance between the two is also a close one inthis respect, that we not only have a general functional dis-ease, which in the one case we call epilepsy and in the otherchorea ; but, like epilepsy, chorea is also frequently enough CHOREA. 121 the expression of actual cerebral disease. It is naturaltherefore to infer that ordinary chorea must be due to dis-turbances similar to those which we find in cases of organiclesion. Almost every conceivable change in brain structurehas been at one time or another held responsible for the de-velopment of chorea. See collected 84 cases of chorea on. Fig. 45.—Dilatation of Blood-vessels in the White Matter of the Convolutions of a veryChronic and Severe Case of Chorea. (Dana.) which a post-mortem examination had been made. In 16no changes were found in the central nervous system, in 32there were lesions in the brain and in the nerve-centres ; inthe remainder there was congestion of the serous mem-branes. Ogle, Pye-Smith, and others refer to a hyperasmiaof the brain and cord. As long ago as 1868 Steiner report-ed upon a careful examination of three cases of chorea. Hefound cerebro-spinal anaemia and some connective-tissueproliferation in the upper part of the spinal cord; conse- 122 THE NERVOUS DISEASES OF CHILDREN. quently he considered chorea to be the result of spinal irri-tation. Meynert and Elischer found hyaline degenerationin the nerve-cells of the central ganglia. The latter authoralso found changes in the vessels of the central ganglia aswell a
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectnervous, bookyear1895
