. The biology of senescence. Old age; Aging; Longevity. The Mechanisms of Senescence which follow gonadectomy, and many of them are reversible by gonadal hormones. (Korenchevsky et aL, 1950; McGavack, 1951). The peripheral effects of sex hormones in senility, such as the recornification of the vagina by oestrogen (Loeb, 1944), are familiar enough. The decrease of mitotic rate and degree of vacuolation in the adrenal (Townsend, 1946; Blumenthal, 1945) and the increase of collagen and reticulum in the capsule MC 16 15 14 13 12 II 10 9 â 8 - 7 ⢠6 â 5 â 4 ⢠\ ><\KIRK,I949 3 2 â I -. -HAMB
. The biology of senescence. Old age; Aging; Longevity. The Mechanisms of Senescence which follow gonadectomy, and many of them are reversible by gonadal hormones. (Korenchevsky et aL, 1950; McGavack, 1951). The peripheral effects of sex hormones in senility, such as the recornification of the vagina by oestrogen (Loeb, 1944), are familiar enough. The decrease of mitotic rate and degree of vacuolation in the adrenal (Townsend, 1946; Blumenthal, 1945) and the increase of collagen and reticulum in the capsule MC 16 15 14 13 12 II 10 9 â 8 - 7 ⢠6 â 5 â 4 ⢠\ ><\KIRK,I949 3 2 â I -. -HAMBURGER,1949 HAMILTON AND HAMILTON, 1948 ROBINSON, 1948 YEARS 40 50 60 70 80 90 Fig. 41.âNeutral 17-Ketosteroids, 24-hour urinary excretion (Kirk 1949). and in the parenchyma (Dribben and Wolfe, 1947) which occur with advancing age are partially reversible by oestrogen, and more fully reversible by a combination of oestrogen, androgen and progesterone (Korenchevsky, Paris and Ben- jamin, 1950). In the pituitary of the senile rat, Wolfe (1943) found a decrease in eosinophils, but no increase in basophils vacuolation, like that which follows castration, occurred in the basophils with increasing age. These changes, particularly the decrease in eosinophils, are at least partially reversed by testos- terone propionate (Wolfe, 1941). The senescent changes in 173. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Comfort, Alex, 1920-. New York, Rinehart
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Keywords: ., bookcentury1900, booksub, booksubjectlongevity, booksubjectoldage
