Manual of pathological anatomy . e long bones, and altera-tions in the shape of the thoraxand pelvis. (5) Arrest of growth,both of the bones and of partsanatomically or physiologicallycorrelated to them. (1) The enlargement of theends of the bones may be con-siderable. In one of Sir cases the circumferenceof the wrist was equal to the length of the forearm, each being4J inches (in a child 30 inches high; three years and two monthsold). The parts thus enlarged are normally somewhat prominentin children, in consequence of the process of ossification which isgoing on; but the rickety en
Manual of pathological anatomy . e long bones, and altera-tions in the shape of the thoraxand pelvis. (5) Arrest of growth,both of the bones and of partsanatomically or physiologicallycorrelated to them. (1) The enlargement of theends of the bones may be con-siderable. In one of Sir cases the circumferenceof the wrist was equal to the length of the forearm, each being4J inches (in a child 30 inches high; three years and two monthsold). The parts thus enlarged are normally somewhat prominentin children, in consequence of the process of ossification which isgoing on; but the rickety enlargement is generally adjacent cartilage is always somewhat enlarged also on theside next the bone. (2) There is, undoubtedly, some general softening of the bones,due apparently to a deficiency of lime, and by this their curvatureis made possible. Virchow, however, alleges that any consider-able curvature in the shaft is always due to some bones have been found to contain only 21 per cent, of. Section cut with a knife of the femurof a rickety child. The shaft consiststhroughout of cartilaginous and gelati-nous substances, intermixed and disposedin cells ; it is observable that a greaterquantity of cartilage exists in the middleof the shaft and towards the interiorcurve than at any other part. (St. Bartholomews Museum, i. 34.) * Medical Times and Gazette, 1860, vol. RIIACHITIS, OR RICKETS. 847 mineral matter, while the bones of healthy children should contain37 per cent. (Jenner). (3) Thickening of the flat bones is due, precisely as in theswelling of the ends of long bones, to hypertrophy of the medul-lary pulp, and expansion of the cancellous tissue. The substanceof the bone seems mainly to consist of diploe (Aitken). In thecranial bones it makes the sutures appear like deep has been supposed that this diminishes the capacity of thecranium. The fontanelles are always late in closing. A peculiarform of disease of the cranium has b
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