National Institutes of Health researchers and international colleagues have discovered a genetic cause and potential treatment strategy for a rare immune disorder called CHAPLE. This light microscope image shows the intestinal tissue of a child with CHAPLE's disease. The large white areas in the lower right corner are enlarged lymphatic vessels, which may contribute to bowel distress.

---

Size: 4091px × 3020px
Location:
Photo credit: © NIH / IMAGE POINT FR / BSIP / Alamy / Afripics
License: Licensed
Model Released: No

Keywords: breakdownpathologysymptomdisordergeneticshistologytissuetreatment, digestive, ductlymph, ductslymph, examination, gastrointestinal, imagerymicroscopeoptical, investigation, medical, micrographlight, microscopeimmunologylymphatic, microscopelight, microscopeslight, microscopesoptical, microscopylmimmunologicimmuneimmunologicalimmune, microscopyphotomicroscopeoptical, systemdigestive, systemlymph, systemlymphatic, systemlymphlymphaticlymphoidlymph, systemlymphoid, techniqueexamination, techniquemedical, techniquemicrographmicrographymiscroscopymicroscopesmicroscopylight, techniques, techniquesimagingmedical, techniquesinvestigation, techniquesmedical, testinvestigation, trackbowelentericintestinal, tractdigestingdigestivedigestiondigestive, tractdigestive, tractgigi, tractintestinalenterongutintestineschildhoodchildrenchildlikechildishkidkidsexamination, tubeintestinechildscientific, vessellymph, vesselnervous, vesselslymphatic