. The pigmentary, growth and endocrine disturbances induced in the aunran tadpole by the early ablation of the pars buccalis of the hypophysis. any secondaryacceleration subsequent to the critical point, while the colloidgroup exhibits an even greater retardation than its fellows sup-plied with Tethelin. In order to further test the growth effects of hypophysectomyand its response to an anterior-lobe diet, a series of experimentssimilar in every way to those just reported upon were carriedout with toad larvae. These larvae respond in general in thesame way as the similarly treated frog tadpole


. The pigmentary, growth and endocrine disturbances induced in the aunran tadpole by the early ablation of the pars buccalis of the hypophysis. any secondaryacceleration subsequent to the critical point, while the colloidgroup exhibits an even greater retardation than its fellows sup-plied with Tethelin. In order to further test the growth effects of hypophysectomyand its response to an anterior-lobe diet, a series of experimentssimilar in every way to those just reported upon were carriedout with toad larvae. These larvae respond in general in thesame way as the similarly treated frog tadpoles. The earlyretardation, the usual midlarval slowing (critical point), fol-lowed by slow growth, appears as in the frog tadpole (fig. 6).In this, my observations are somewhat at variance with thoseof Allen, who reports no retardation in the velocity of growthin hypophysectomized toads. Fuller reports may explain thisessential difference in our results. I wish to emphasize, how-ever, that the early retardation, the critical point, and thelater period of slow growth are not so distinctly shown in the 56 PIGMENTARY GROWTH AFTER ABLATION OF. Fig. 3 Growth curves of hypophysectomized frog larvae supplied with freshanterior-lobe substance, with aqueous extract, and with aqueous residue of theanterior lobe. The ordinates represent the total length of the larvae expressed inmilUmeters. THE PARS BUCCALIS OF THE HYPOPHYSIS 57


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Keywords: ., bookcentury1900, bookdecade1920, booksubjectfrogs, bookyear1920