. Cellular basis and aetiology of late somatic effects of ionization radiation. Radiation -- Physiological effect. RADIATION-INDUCED LIFE-SPAN SHORTENING IN MICE 281 might therefore be more correct to look upon radiation as bringing about a new late somatic change which is quite absent in the unirradiated population. Another characteristic pathological change occurring with advancing age in several strains of mice, including ours, is to be found in tlie kidney. The condition is described under several names in the literature, but for the CBA 50 25 llOOr Control Limiting value obtained from pre
. Cellular basis and aetiology of late somatic effects of ionization radiation. Radiation -- Physiological effect. RADIATION-INDUCED LIFE-SPAN SHORTENING IN MICE 281 might therefore be more correct to look upon radiation as bringing about a new late somatic change which is quite absent in the unirradiated population. Another characteristic pathological change occurring with advancing age in several strains of mice, including ours, is to be found in tlie kidney. The condition is described under several names in the literature, but for the CBA 50 25 llOOr Control Limiting value obtained from previous studies in which animals were allowed to die. 9 12 15 Age (months) Fig. 3. Incidence of lung tumours with increasing age in serially killed control and X-irradiated CBA male mice. animals, the term papillonephritis, as defined by Dunn (1944), is thought to be most applicable. The effect of the radiation treatment on the series of developmental changes leading to papillonephritis, as seen in the control mice, is different, yet again, from the other examples quoted above. From 6 months of age, when the first pathological changes become visible, the steady. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Harris, R. J. C. (Robert John Cecil), 1922-; Unesco; International Atomic Energy Agency. London, New York, Academic Press
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