. Control of ovulation; proceedings of the conference held at Endicott House, Dedham, Massachusetts, 1960. Ovulation -- Regulation. Area common to lesions in 8 rats Sagittal section. Ventral view Fig. 6. portion of the hypothalamus. In my laboratory, Mr. Gellert has been working on this problem for two years. Because true precocious puberty is properly defined as the early onset of otherwise normal sexual cycles, we have produced lesions in various parts of the brain in immature female rats, and then followed them and their controls until all were cycling. By serially sectioning the brains, we
. Control of ovulation; proceedings of the conference held at Endicott House, Dedham, Massachusetts, 1960. Ovulation -- Regulation. Area common to lesions in 8 rats Sagittal section. Ventral view Fig. 6. portion of the hypothalamus. In my laboratory, Mr. Gellert has been working on this problem for two years. Because true precocious puberty is properly defined as the early onset of otherwise normal sexual cycles, we have produced lesions in various parts of the brain in immature female rats, and then followed them and their controls until all were cycling. By serially sectioning the brains, we have located the lesion in each of the animals and then divided the animals into groups on the basis of common areas of destruction. In Fig. 5, the mean age for vaginal opening and onset of first estrus are shown for normal controls, animals with lesions in the anterior hypothalamus, animals with lesions elsewhere in the brain, and animals with a common area of. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Harvard University; Association for the Aid of Crippled Children; Villee, Claude Alvin, 1917-. New York, Symposium Publications Division, Pergamon Press
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