. Chemical embryology. Embryology. SECT. 12] CYCLOSES, PHOSPHORUS, SULPHUR 1231 inositol, instead of a hexaphosphate, but at present there is no reason for supposing that such compounds exist in the body. In order to get some insight into the precursor of inositol, Needham injected a series of unincubated eggs with various substances, phytic acid, hexamethylenetetramine (to test the hypothesis of Posternak who suggested that inositol might arise from the condensation of six molecules of formaldehyde) and glucose. Tests showed subsequently 600q 500- + 250 mg. glucose 250 mg. glucose 300-. â = e
. Chemical embryology. Embryology. SECT. 12] CYCLOSES, PHOSPHORUS, SULPHUR 1231 inositol, instead of a hexaphosphate, but at present there is no reason for supposing that such compounds exist in the body. In order to get some insight into the precursor of inositol, Needham injected a series of unincubated eggs with various substances, phytic acid, hexamethylenetetramine (to test the hypothesis of Posternak who suggested that inositol might arise from the condensation of six molecules of formaldehyde) and glucose. Tests showed subsequently 600q 500- + 250 mg. glucose 250 mg. glucose 300-. â = embryo O = remainder + 725 mg. glucose Normal Normal and + 125 mg. glucose f 250 mg. lieKamethylene-tetramina âr- 20 Fig. 396. the presence of formaldehyde in the egg-interior after injection of hexamethylenetetramine, but neither the eggs which had received phytic acid nor those which had received hexamethylenetetramine could be got to develop normally. Doubtless the highest concentration compatible with normal development could have been found by further searching, but, in view of the positive results obtained with glucose, this was not undertaken. For, as Fig. 396 shows, injection of glucose markedly increased the inositol content of the embryo, though not of the rest of the egg. It would therefore seem likely that the synthesis of inositol from glucose only takes place within the embryo. The existence of this synthesis in the developing embryo agreed with. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Needham, Joseph, 1900-. New York: The MacMillan Co.
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Keywords: ., bookcentury1900, bookpublishernewyorkthem, booksubjectembryology
