A practical treatise on urinary and renal diseases : including urinary deposits . rolonged boiling was found byStrecker to lessen the solubility of xanthine in hot * Journ. of Chemical Society, Feb. 1862, p. 79. It may be remarked thatin 110 previous account of xanthine have crystals of that substance been is to be wished that in Dr. B. Joness case the identification of xanthine hadbeen more perfect. f Strecker : Liebigs Ann., May, 1861, Bd. cxviii. p. 158. X Ibid., p. 168. See also a recent paper Sur la Xanthine et sa recherchedans les calculs vesicaux, Lebon. Comptes Rendus,
A practical treatise on urinary and renal diseases : including urinary deposits . rolonged boiling was found byStrecker to lessen the solubility of xanthine in hot * Journ. of Chemical Society, Feb. 1862, p. 79. It may be remarked thatin 110 previous account of xanthine have crystals of that substance been is to be wished that in Dr. B. Joness case the identification of xanthine hadbeen more perfect. f Strecker : Liebigs Ann., May, 1861, Bd. cxviii. p. 158. X Ibid., p. 168. See also a recent paper Sur la Xanthine et sa recherchedans les calculs vesicaux, Lebon. Comptes Rendus, lxxiii. 47. 92 INORGANIC DEPOSITS. VIII.—LEUCINE AND TYROSINE. These two substances were found by Stadeler and Frerichsin the urine in typhoid fever and acute yellow atrophy of theliver. Tyrosine has even been found to form a natural urinarydeposit in the latter disease. This deposit is described byFrerichs as a greenish-yellow crystalline sediment, which in-creases considerably with slight evaporation of the the microscope, greenish-yellow globulur masses, com-. Pig. 1G. Tyrosine, spontaneously deposited from the urine of a patient with acuteyellow atrophy of the liver. posed of acicular crystals are seen. In one of Frerichs casesof acute yellow atrophy, he says of the urine :— After stand-ing in the cold air, a greenish-yellow light sediment wasdeposited, consisting entirely of acicular crystals of tyrosineaggregated together in globular masses. When a drop of urinewas evaporated on a watch-glass, it left behind a residuum,which, upon microscopical examination, was found to be almostexclusively composed of the most characteristic possible crys-tals of leucine and tyrosine, partly saturated with colouringmatter. * Frerichs regards the occurrence of these depositsas of great importance in the diagnosis of acute yellow atrophyof the liver. In May, 1865, my assistant, Mr. Clements, brought me a * Frerichs on Dis. of Liver, Syd. Soc. Trans., vol. i., Frontispiece,
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