. Basic mechanisms in radiobiology. 11 understood you correctly, the charge is passed along the bonds until you sort of get to the outside, to the periphery, and in that condition these two things that you mentioned can occur. POLLARD: Actually what I want to do is to make Augenstine's third point, and that is that some place a new bond must be capable of formation. This molecule isn't inactivated until it has gone wrong. If the molecular pattern is undisturbed, it will recover within 10"° seconds. But if something has been broken that can form a wrong configuration, that is the thing tha
. Basic mechanisms in radiobiology. 11 understood you correctly, the charge is passed along the bonds until you sort of get to the outside, to the periphery, and in that condition these two things that you mentioned can occur. POLLARD: Actually what I want to do is to make Augenstine's third point, and that is that some place a new bond must be capable of formation. This molecule isn't inactivated until it has gone wrong. If the molecular pattern is undisturbed, it will recover within 10"° seconds. But if something has been broken that can form a wrong configuration, that is the thing that inactivates the molecule. As I have indicated here, the serious events take place at the periph- ery, but that might not necessarily be the case if you have a helical structure that is bonded in a certain way. The bonding might go inside and instead of the helix holding it in place, you would have r momentary deformation of the helix that stays there. So that the site where wrong bonding occurs is the place where radiation action is finally manifest. The other concept I have is the free travel of this type of energy -- you can think of it either as a broken bond, as surplus charge, or lack of charge -- free travel up and down. BARRON: The theory of the electron traveling through the protein structure was formulated by Schmidt in an article published 3 years ago, and since then Franck and Livingston (9) have said that no such thing exists. PLATZMAN: The discussion by Franck and Livingston has nothing to do with what Dr. Pollard is proposing. It was specifically restricted to the con- sequences of electronic excitation -- , by light absorption, and was not con- cerned with consequences of ionization by ionizing radiation. POLLARD: I am not speaking of an electron traveling and I am not speaking of a proton of a nucleus traveling. I am speaking of the location where there is positive electricity. BARRON: Do you mean then, that it is thB amino group, because you have a prot
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