. The thyroid gland in health and disease. ^in the neighbourhood of the nucleus (figs. 11, 12, 13). Desquamation of the vesicular epithelium may occur, partor the whole of the cell being discharged into the acinar cavity. A characteristic feature of the cells at this stage, and one inwhich it is in marked contrast to the normally secreting cells, is. Fig. 10.—Section of thyroid gland from early case of Graves Disease, showinggreat congestion of capillaries, high columnar epithelium lining the irregularly shapedvesicle, absence of stainable colloid, and blood corpuscles and cellular debris inve


. The thyroid gland in health and disease. ^in the neighbourhood of the nucleus (figs. 11, 12, 13). Desquamation of the vesicular epithelium may occur, partor the whole of the cell being discharged into the acinar cavity. A characteristic feature of the cells at this stage, and one inwhich it is in marked contrast to the normally secreting cells, is. Fig. 10.—Section of thyroid gland from early case of Graves Disease, showinggreat congestion of capillaries, high columnar epithelium lining the irregularly shapedvesicle, absence of stainable colloid, and blood corpuscles and cellular debris invesicle. From a specimen in the possession of the late Sir Victor Horsley, the striking variation in size, shape and staining characters ofthe parenchyma nuclei. Some are much enlarged, and may beeither deeply stained, hyper-chromatic or vesicular; thesenuclei are oval or spherical in outline, and may measure 8 to 10 /xin diameter. Others are small, intensely staining or pale-stain-ing ; these rejiresent recent-division forms. Others are irregular,kidney-shaped or pyriform. These diverse nuclear appearancesare the evidence of abnormal cell-division. Mitotic figures areoccasionally met with, especially in young glands. These HISTO-PATHOLOGY 63 changes have been observed in experimentally-produced goitrein rats [19]. 4. The cellular incr


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Keywords: ., bookcentury1900, bookdecade1910, bookpublishernewyorkwilliamwood