. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 258 DEMOREST DAVENPORT In a heart which had been treated with atropine 1: 10,000 for fifteen minutes the response to muscarine 1: 5,000 was completely abolished. EFFECTS OF DORYL (CARBAMINOYLCHOLINE) Bonnet (1937) observed the effects of the sympathomimetics, doryl and mecholyl, on the heart of the crayfish while investigating the antago- nism between strychnine and acetylcholine in these animals. Mecholyl was found to accelerate the crayfish heart while doryl in the concentra- tions used retarded it. Bonnet's results are, h
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 258 DEMOREST DAVENPORT In a heart which had been treated with atropine 1: 10,000 for fifteen minutes the response to muscarine 1: 5,000 was completely abolished. EFFECTS OF DORYL (CARBAMINOYLCHOLINE) Bonnet (1937) observed the effects of the sympathomimetics, doryl and mecholyl, on the heart of the crayfish while investigating the antago- nism between strychnine and acetylcholine in these animals. Mecholyl was found to accelerate the crayfish heart while doryl in the concentra- tions used retarded it. Bonnet's results are, however, not strictly com- parable to the present work since his drugs were applied directly to the heart in situ with nervous connections intact. B. Doryl 1:2000 ^H FIG. 2. A, Effect of muscarine 1: 5,000. B. Effect of doryl 1 : 2,000. In the heart of Cancer doryl 1:1,000,000 increases frequency and amplitude. This effect becomes more marked as higher concentrations are used. In no tests, however, even when concentrations as high as 1 : 2,000 were used (Fig. 2B] was it found possible to produce the marked increase in tone resulting in systolic tetany, characteristic of high con- centrations of acetylcholine or nicotine. In a number of tests it was found that previous treatment with atro- pine 1: 10,000 had no effect on the response to high concentrations of doryl (1:2,000). In one test, however, a heart responded to doryl 1: 1,000,000 with an increase in frequency and amplitude. Treatment with atropine 1: 10,000 abolished this response when the doryl was. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marine Biological Laboratory (Woods Hole, Mass. ); Marine Biological Laboratory (Woods Hole, Mass. ). Annual report 1907/08-1952; Lillie, Frank Rattray, 1870-1947; Moore, Carl Richard, 1892-; Redfield
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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology
