. Electrolytes in biological systems, incorporating papers presented at a symposium at the Marine Biological Laboratory in Woods Hole, Massachusetts, on September 8, 1954 . Millivolt 20 40 60 80 100 120 Fig. 14. Dependence of net chloride (NaCl) transport across skin upon sivin potential. Calcium-free Ringer's solution on both sides of the skin. Rana pipiens (28). crease of sodium influx with increasing spontaneous skin potential was seen by Fuhrman and Ussing (8). Although this type of relationship is theoretically quite possible, it is somewhat puzzling, since under similar experimental con-


. Electrolytes in biological systems, incorporating papers presented at a symposium at the Marine Biological Laboratory in Woods Hole, Massachusetts, on September 8, 1954 . Millivolt 20 40 60 80 100 120 Fig. 14. Dependence of net chloride (NaCl) transport across skin upon sivin potential. Calcium-free Ringer's solution on both sides of the skin. Rana pipiens (28). crease of sodium influx with increasing spontaneous skin potential was seen by Fuhrman and Ussing (8). Although this type of relationship is theoretically quite possible, it is somewhat puzzling, since under similar experimental con- ditions Koefoed-Johnsen, Levi and Ussing (39), as well as other workers (28, 46), have found decreasing Cl~ influx, outflux and net flux with increasing spon- taneous skin potential (fig. 14). The correlation between skin potential and active salt transport can also be deduced from two useful equations derived by Linderholm (45):


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