. Calcified tissues; proceedings. Bone; Collagen; Calcification. MUSCLE TONE -1 Fig. 5. Diagram ,.1 lonslup ,.t ,.ni,il tooth. Center sketch depicts biting, fibers are taut. At right, tooth is being moved by force which tightens periodontal fibers at trailing surface of root where osteoblastic activity occurs and slac-kens libers at leading surface, where osteoclasts are removing bone If osteoclasts occur in regions where the electrical signal is diminished or absent, it should be possible to find a common electrical link between factors known to cause osteolysis. For example, al


. Calcified tissues; proceedings. Bone; Collagen; Calcification. MUSCLE TONE -1 Fig. 5. Diagram ,.1 lonslup ,.t ,.ni,il tooth. Center sketch depicts biting, fibers are taut. At right, tooth is being moved by force which tightens periodontal fibers at trailing surface of root where osteoblastic activity occurs and slac-kens libers at leading surface, where osteoclasts are removing bone If osteoclasts occur in regions where the electrical signal is diminished or absent, it should be possible to find a common electrical link between factors known to cause osteolysis. For example, although it has been stated that bone removal depends on vascular changes (Geiser and Trueta, 1958), it is not entirely clear yet whether they are attendant upon or responsible for the removal. If, as Johnson (1964) believes, active hyperemia causes bone destruction, it might do so by providing more electron "sinks" through hyperoxia or streaming potentials. Arterial walls are positively charged on the adventitial surface and negatively charged on the endothelial (Sawyer and Pate, 1953). It is conceivable, therefore, that the erosion of bone by an aneurysm may be electri- cally mediated, since the vessel wall could conduct away more electrons than were generated by deformation. Finally, since it appears likely that bone mass and orientation may be con- trolled by stress-generated electrical po- d, . c 1-1 fig. ''. four sources ,it iiu-cnaiiKii input ti> normal s, the origin of mechanical stresses skeleton in the skeleton deserve brief attention. Actually, bone may function in a manner similar to an exquisitely sensitive, piezo- electric accelerometer, responding to the slightest jar or deformation. There are four main sources of mechanical input for the skeleton (Fig. 6). The cardiovascular system provides a continual deforming force (Gebhardt, 1905) through hydrostatics in the. Please note that these images are extracted from scanned page images that may have


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