Physiology and biochemistry in modern medicine . ctions. Incases where the existence of inhibitory fibers is doubtful, great aid isafforded by the use of ergotoxine, an alkaloid of ergot, which possessesthe remarkable property of specifically paralyzing Hie augmentor nervesof the sympathetic system (but not of the parasympathetic); that is,the same fibers as are stimulated by epinephrine. When a particularstructure is supplied with augmentory and inhibitory fibers by a com-bined sympathetic nerve, electric stimulation or the application of epi-nephrine usually gives only augmentory effects; af
Physiology and biochemistry in modern medicine . ctions. Incases where the existence of inhibitory fibers is doubtful, great aid isafforded by the use of ergotoxine, an alkaloid of ergot, which possessesthe remarkable property of specifically paralyzing Hie augmentor nervesof the sympathetic system (but not of the parasympathetic); that is,the same fibers as are stimulated by epinephrine. When a particularstructure is supplied with augmentory and inhibitory fibers by a com-bined sympathetic nerve, electric stimulation or the application of epi-nephrine usually gives only augmentory effects; after the injection of Pilo motor ,nuscle Lachrymal_c[land -^Ciliary gang *~s^ gang. Nasal mucosa ,-—^ Parotid gland-gland r j Submaxillary glan Submaxillary(Sublingual)ganglion Cranial and Sacral nervesmotor = redinhibitory = blue Thoraclco-lumbar nerves Postganglionic fibersare dotted,thus—- Sup. cervical ganglion Thyroid gland Infxervical ganglionT-Ansa subclavia -SteJIate (i*J Thoracic)ganglion Sweat gland. lliocecalsphincter Bladder Vesical sphincter Urethral sphincter ^-Vasomotorfibers Pilo motor muscle Celiac (Semilunar) ganglion(Solarplex)Splanchnic nerves ^^Sympathetic chain Lumbar splanchnics Sup. Mesenteric ganglion Inf. Mesentericganglion hypogastric nerves Pelvic(HypogastricJnterUidc)plexus. {Vesicals, rectal portions) Pelvicnerves {Nervus erigens) 7? P HailecK Fig. 23i.—Schematic representation of the involuntary nervous system. (From Jackson.) THE AUTONOMIC NERVOUS SYSTEM 88) ergotoxine, however, a reversed effed is observed; namely, inhibitioninstead of augmentation. By taking advantage of this fact, Dale 1msbeen able to demonstrate in the hypogastric nerves inhibitory fibers tothe uterus, and Elliotl lias demonstrated the inhibitory action of epi-nephrine on the muscles of the ureter in the dog. Inhibitory fibers havealso been discovered by these methods in the great splanchnic nerves, inthe nerve routs supplying the kidney,
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