. A manual of diseases of the nervous system. rhaps the leastdangerous to life of any chronicspiaal disease. Even secondarykidney trouble scarcely ever oc-curs; perhaps the excessive re-flex action may save the bladderfrom injurious is when other elements ofthe cord suffer that dangerouscomplications ensue. PATHOLOGICAIi AkATOMT.—In the fact just stated we probablyhave an explanation of the silence of morbid anatomy on the subject ofuncomplicated lateral sclerosis. Nee silet mors, the apt motto of thePathological Society, is true chiefly of disease that kills. Completedegene
. A manual of diseases of the nervous system. rhaps the leastdangerous to life of any chronicspiaal disease. Even secondarykidney trouble scarcely ever oc-curs; perhaps the excessive re-flex action may save the bladderfrom injurious is when other elements ofthe cord suffer that dangerouscomplications ensue. PATHOLOGICAIi AkATOMT.—In the fact just stated we probablyhave an explanation of the silence of morbid anatomy on the subject ofuncomplicated lateral sclerosis. Nee silet mors, the apt motto of thePathological Society, is true chiefly of disease that kills. Completedegeneration of the pyramidal tracts, anterior as well as lateral, ismet with chiefly in cases in which the anterior ganglion-cells and motornerves are also diseased, although in some instances the amount ofthis disease is small, and limited to the cervical region. Aa instance * Charcot, Progrfts M6dicaV 1891. t I am indebted for these sections to Dr. Dreschfeld, who has published the case(« British Med. Journal.,* Jan. 29fch, 1881). VOL. 1. 32. Pia. 133.—Sclerosis of the lateral and (inthe cervical region anterior) pyramidaltracts, with slight degeneration of theanterior cornua. A, cervical; B, dor-sal; C, lumbar 498 SPINAL CORD. of sucli degeneration is shown in Fig 133, Tlie degeneration in thelumbar enlargement is usually limited to the lateral tract, but theanterior tract may be affected higher up the cord, as in Fig. 133, A. Thelateral sclerosis is bounded externally, in the dorsal and cervicalregions, by the normal direct cerebellar tract, and internally by thenarrow lateral limiting layer which intervenes between the pyra-midal tract and the intermediate grey matter There is the usualincrease of connective tissue and wasting of nerve-fibres. In manycases granule-cells are abundant in the affected area. They arealways present in cases of short duration, and indicate the stagerather than the nature of the process. The degeneration probablybegins in all cases in
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