Practical physiological chemistry; a book designed for use in courses in practical physiological chemistry in schools of medicine and of science . tinue the series. This procedure has theadvantage of being speedy and accurate. There is a slight error made by the rapid additionof the NaOH but it is uniform and the results (titrations) are therefore comparable. GASTRIC ANALYSIS 163 Calculation.—Note the number of cubic centimeters of N/100 NaOH requiredto neutralize i of stomach contents, and multiply it by 10 to obtain the numberof cubic centimeters N/io NaOH necessary to neutralize 100 c.


Practical physiological chemistry; a book designed for use in courses in practical physiological chemistry in schools of medicine and of science . tinue the series. This procedure has theadvantage of being speedy and accurate. There is a slight error made by the rapid additionof the NaOH but it is uniform and the results (titrations) are therefore comparable. GASTRIC ANALYSIS 163 Calculation.—Note the number of cubic centimeters of N/100 NaOH requiredto neutralize i of stomach contents, and multiply it by 10 to obtain the numberof cubic centimeters N/io NaOH necessary to neutralize 100 of stomachcontents. This is the method of calculation most widely used. For other formsof expressing total acidity see page 174. Plot your results in a form similar tothose shown in Figs. 45 and 46. Curves Obtained by the Fractional Method.—When an Ewald test mealis given to normal individuals a curve such as indicated below is usu-ally obtained. The curve may vary within certain limits depending onindividual idiosyncrasies, but is usually found to follow the curvedepicted, and the meal normally leaves the stomach in two and one- iOO. 20 40 60 60 100 120 Fig. 45.—Acidity Curves of XoRiiAL Human Stomach. half hours. Pathologically every variation occurs, both in time ofevacuation as well as the character of the curve and the quantity of thesecretion elaborated. Fig. 41 represents some of the possibilities ofpathological cases, but a consideration of their interpretation is outsidethe purpose of the present volume. It will be evident, however, froma consideration of the figure that the cycle of gastric digestion is a con-stantly changing one, and no information concerning the trend ofdigestion can be obtained by an examination of only a single stage ofdigestion. Marked changes may precede or follow that stage and thepossibilities suggested in Fig. 41 are all observed clinically and are ofvarying significance. Typical curves from cases of hyperacidity,gastric carcinoma an


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