American journal of physiology . Figure 1. Experiment I. Shows the absence of effect on rate or size of beat fromchanging from normal perfusion to a perfusion solution containing extract ofresting muscle (i cc. of extract to 40 cc. Lockes solution containing defibrinatedblood). In this and succeeding figures the lower line marks the time in intervalsof one second. The upper line is a suspension curve of the ventricles, the up-stroke of which represents systole. All records read from left to right. The markX indicates the change from normal perfusion to perfusion with the Figure 4A. E
American journal of physiology . Figure 1. Experiment I. Shows the absence of effect on rate or size of beat fromchanging from normal perfusion to a perfusion solution containing extract ofresting muscle (i cc. of extract to 40 cc. Lockes solution containing defibrinatedblood). In this and succeeding figures the lower line marks the time in intervalsof one second. The upper line is a suspension curve of the ventricles, the up-stroke of which represents systole. All records read from left to right. The markX indicates the change from normal perfusion to perfusion with the Figure 4A. Experiment IV. Increase of size of beat as a result of perfusion withblood from tetanized animal. The change to fatigue blood was made at X. Theincrease in size of contraction is mainly due to increased relaxation in diastole.
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