Transactions of the Royal Society of Edinburgh . in at a. 192 PROFESSOR RUTHERFORD ON THE Necropsy.—There was slight congestion of the upper part of the smallintestine to the extent of about 10 inches. In the duodenum the mucousmembrane had a yellowish-grey appearance, as if it had been slightly corrodedby an acid. There was no evidence of any purgative effect. Results of Experiments with Nitro-hydrochloric Acid.—The positive effectof the acid in Experiment 44a is in remarkable contrast to the negative resultobserved in Experiment 44. In consequence of the positive result in the former case, a
Transactions of the Royal Society of Edinburgh . in at a. 192 PROFESSOR RUTHERFORD ON THE Necropsy.—There was slight congestion of the upper part of the smallintestine to the extent of about 10 inches. In the duodenum the mucousmembrane had a yellowish-grey appearance, as if it had been slightly corrodedby an acid. There was no evidence of any purgative effect. Results of Experiments with Nitro-hydrochloric Acid.—The positive effectof the acid in Experiment 44a is in remarkable contrast to the negative resultobserved in Experiment 44. In consequence of the positive result in the former case, and seeing that it com-pletely agrees with observa-tions on man, we did not thinkit necessary to perform anotherexperiment. In view of thepositive effect in 44a, we donot attach any importance tothe negative result of Experi-ment 44; for the animal wasa small one, and in such caseswe have found that undoubtedcholagogues sometimes failto act. It is proved, then,that dilute nitro-hvdrochloricacid is a hepatic stimulant ofconsiderable power. 05. Fig. 45.—Secretion of bile before and after sodium chloride. 10 injected into duodenum at w. The same with 120 grainssodium chloride injected ats, sf, s, s (480 grains given in all). Experiment 45. Secretion Secretion Secretion of bile per Secretion of bile per of bile per kilogramme of bile per kilogramme 15. of dog : per 15. of dog: per hour. hour. cc. cc. 1-82172 1-902-00 | 0-306 cc. 1-82 1-80 172 s w 1-85 172 \ 2-10 <-0346ce. 1751-80 VO-28 cc. 2-15 2-20 1-75 J 2 22 J s 2-00 1-70 2-15 1-70 2-00 175 s 175 1-90 s 1-90 175 2-00 1-851-90 | 0-306 cc. 1-80 45). Action of Sodium Chloride. Sodium chloride is a cath-artic when given in doses of 120to 240 grains. It is not statedto be a cholagogue, but as itis contained in considerablequantity in the mineral watersof Carlsbad, Ems, Friedrich-shall, that have a reputationin abnormal conditions of theliver, we thought it desirableto test its action on this organ. Experiment 45. Dog
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