Materia medica and therapeutics : for physicians and students . eae), a small indigenous plant, with radical, cor-date, lobate leaves and a handsome white eight-petaled flower,which appears in early spring, is usually classed with dried it is in flattened pieces, much wrinkled and contorted,of a reddish-brown color, with a faint narcotic odor and bitterish,very acrid taste. It yields its virtues to water and alcohol, andloses them rapidly by keeping. An alkaloid, sangtdnarine(C19HJ7NO4), has been obtained from it which possesses the prop-erties of the root. Effects and Uses.—Blood
Materia medica and therapeutics : for physicians and students . eae), a small indigenous plant, with radical, cor-date, lobate leaves and a handsome white eight-petaled flower,which appears in early spring, is usually classed with dried it is in flattened pieces, much wrinkled and contorted,of a reddish-brown color, with a faint narcotic odor and bitterish,very acrid taste. It yields its virtues to water and alcohol, andloses them rapidly by keeping. An alkaloid, sangtdnarine(C19HJ7NO4), has been obtained from it which possesses the prop-erties of the root. Effects and Uses.—Bloodroot is an acrid emetic, and, in largedoses, an acro-narcotic poison. Locally, it acts as an irritant, andupon fungous surfaces, as an escharotic. When inhaled, the 3i6 MATERIA MEDICA ECCRITICS. powder causes violent sneezing. In large doses it causes collapse,dilated pupil, and sometimes convulsions of spinal origin, anddiminishes reflex activity. After nauseating doses the pulse andarterial pressure are increased, but when enough is taken to pro- FlG, SANGUINARIA CANADENSIS. duce vomiting the pulse is slow and irregular and the arterialtension is lowered. After poisonous doses the respirationbecomes shallow and slower, and death takes place from asphyxia,due to paralysis of the respiratory centre. EMETICS APOMORPHINE HYDROCHLORATE. 317 Sanguinaria* produces salivation and increases the secretion ofthe gastric mucous membrane. It stimulates the liver and intes-tinal glands, increasing the secretion of bile, but at the same timerendering it more watery (Rutherford). It is an active systemicemetic, causing much depression and irritation of the mucousmembrane. It is not much used as an emetic, but is occasionallyemployed with this view in croup and diphtheria, or as an expec-torant in pulmonary affections. In duodenal catarrh and second-ary catarrhal jaundice it has been used with advantage. It hasalso been used as an emmenagogue in amenorrhoea. Dose, asan emetic, gr. x-xx
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