. The elements of pathological histology with special reference to practical methods . ration, whereas in all other forms of atrophy it maybe either unaltered, in a state of cellular infiltration, or transformedinto adipose tissue (Fig. 192, g). The fatty metamorphosis in somecases sets in even hefore the atrophy of the muscle-fibres, the latterbeing afterwards destroyed merely by the pressure of the growingadipose tissue, a phenomenon which is observed especially in themuscles of the thigh and leg in certain forms of juvenile muscularatrophy, and in which the muscles apparently increase in vo
. The elements of pathological histology with special reference to practical methods . ration, whereas in all other forms of atrophy it maybe either unaltered, in a state of cellular infiltration, or transformedinto adipose tissue (Fig. 192, g). The fatty metamorphosis in somecases sets in even hefore the atrophy of the muscle-fibres, the latterbeing afterwards destroyed merely by the pressure of the growingadipose tissue, a phenomenon which is observed especially in themuscles of the thigh and leg in certain forms of juvenile muscularatrophy, and in which the muscles apparently increase in volume— MUSCULAR HYPERTROPHY 879 hence the designation of pseudo-hypcrtropliic paralysis, or, more cor-rectly, pseitdo-hypcrtropMc lipomatous atrophy of muscle. As regards the muscle corpuscles, in the forms of atrophy justdescribed they are either at once destroyed, or, on the contrary, takeon active growth, giving rise to mononuclear or polynuclear cellslying in rows or in large aggregations, and w^hich sometimes havenuclei of remarkable size (Figs. 190, h, and 192, d and e). The. Fia. 192.—Pigmentary Atrophy and Fatty Growth of the Soleus Muscle inChronic Anterior Poliomyelitis. Part of transverse section through a muscle 285. (Hfematoxylin and eosin.) a, Interstitial connective tissue ; 6, Atrophic primi-tive muscle bundles ; c, Atrophic primitive bundles, with accumulation of pigment, andpartly also showing growth of the nuclei of the sarcolemma; d, Tubes of sarcolemma,with proliferated nuclei and atrophied remnants of the contractile substance ; e, Sarco-lemma tube, now filled only with proliferated nuclei; r, Collapsed sarcolemma tubescontaining nothing but pigment; g, Fat cells. latter process appears to be of a regenerative nature, since it alsodevelops after injuries and necroses of the muscles. Thus longspindle cells may then develop from the proliferated muscle-cor-puscles, from which spindle cells new muscle-fibres are formed, thenuclei continuing to mul
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectpatholo, bookyear1895
