Bacteriophage T4
Bacteriophage T4 has a very efficient mechanism for infecting cells. The key component of this process is the baseplate, located at the end of the phage tail, which regulates the interaction of the tail fibres and the DNA ejection machine. A complex of gene product (gp) 5 (63K) and gp27 (44K), the central part of the baseplate, is required to penetrate the outer cell membrane of Escherichia coli and to disrupt the intermembrane peptidoglycan layer, promoting subsequent entry of phage DNA into the host.
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Photo credit: © Phil Degginger / Alamy / Afripics
License: Licensed
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Keywords: bacteriophage, beta-helix, cell, enterobacteria, molecule, peptidoglycan, phage, structure, t4, triple-stranded
