Diagnostic methods, chemical, bacteriological and microscopical : a text-book for students and practitioners . rogony). The cycle of development of the malarial organism has been more closelyfollowed in the mosquito in the case of the estivo-autumnal parasite. Forany development to occur within the body of the mosquito it is necessarythat the macrogamete become fertilized, so that the course in the mosquitois one of sexual development. The microgametocytes throw out their flagella(microgametes) and the macrogamete ripens in the stomach of the mosquito bycasting off karysomes (polar bodies cons
Diagnostic methods, chemical, bacteriological and microscopical : a text-book for students and practitioners . rogony). The cycle of development of the malarial organism has been more closelyfollowed in the mosquito in the case of the estivo-autumnal parasite. Forany development to occur within the body of the mosquito it is necessarythat the macrogamete become fertilized, so that the course in the mosquitois one of sexual development. The microgametocytes throw out their flagella(microgametes) and the macrogamete ripens in the stomach of the mosquito bycasting off karysomes (polar bodies consisting of chromatin), and in so doingcauses the formation of a slight mound at one portion of the organism throughwhich the free flagellum enters. This process occurs in from one to one anda half hours after the mosquito has bitten a patient infected with malaria. Thenuclear material of the macrogamete and microgamete then unite. The cellthen forms a distinct motile spindle shape called the vermiculus or ookinet. Thesize of this fertilized macrogamete is from 20 microns up and may be found in PLATE EsTivo—Autumnal Parasite. (Wrights Stain) ?^.- THE BLOOD. 545
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