Transactions of the Medical Society of the State of North Carolina [serial] . ncommon. The chief chemical constituent of these stones is calciumcarbonate. The fact that normal pancreatic secretion contains no calciumcarbonate makes it reasonable to assume that an altered secretion pre-cedes stone formation. It is reasonable to conclude that alteration of thepancreatic secretion by infection or pancreatitis, plus stasis, is the causeof stone formation. It has been shown experimentally by Mann andGrorno that the reflux of bile into the pancreatic duct is not a commonfactor in the etiology of pan
Transactions of the Medical Society of the State of North Carolina [serial] . ncommon. The chief chemical constituent of these stones is calciumcarbonate. The fact that normal pancreatic secretion contains no calciumcarbonate makes it reasonable to assume that an altered secretion pre-cedes stone formation. It is reasonable to conclude that alteration of thepancreatic secretion by infection or pancreatitis, plus stasis, is the causeof stone formation. It has been shown experimentally by Mann andGrorno that the reflux of bile into the pancreatic duct is not a commonfactor in the etiology of pancreatitis. Infection in the gall-bladder andducts appears to be the important factor, since it is common knowledgethat there is intimate connection between the lymphatics of the gall-bladder and the pancreas, and inflammatory condition of these two organsare not infrequently associated. The symptoms produced by pancreatic stones are similar to thoseproduced by stones in the biliary tract, and in addition, those of pan- 282 THE MEDICAL SOCIETY OF THE STATE OF NORTH CAROLINA. SURGERY 283 ^/l/iT/?
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