. The Biochemical journal, 1906. Biochemistry. 'CING POWER OF ANIMAL ^qy The structural c]ianu:c in\(»h-cd is slmwu h\- the following' formulae :— 'C\-K /CX-K Soluble Prussian blue undergoes the same chemical change when treated with alkaline solutions of organic reducers, , hydroquinone -or pyrogallol, so that the tissues may be regarded from the bio- chemical standpoint as alkaline reducers. The pale green or colourless compound in the vessels of an injected organ may be restored very rapidly to the vivid blue condi- tion hv irrigation with ,, just as a piece of Prussi
. The Biochemical journal, 1906. Biochemistry. 'CING POWER OF ANIMAL ^qy The structural c]ianu:c in\(»h-cd is slmwu h\- the following' formulae :— 'C\-K /CX-K Soluble Prussian blue undergoes the same chemical change when treated with alkaline solutions of organic reducers, , hydroquinone -or pyrogallol, so that the tissues may be regarded from the bio- chemical standpoint as alkaline reducers. The pale green or colourless compound in the vessels of an injected organ may be restored very rapidly to the vivid blue condi- tion hv irrigation with ,, just as a piece of Prussian blue gelatine ' bleached ' to the leuco state by pyrogallol can be completely ' revived ' by the same treatment. This revival can be brought about more slowly by exposure to the air ; the colourless condition becoming pale green, the pale green becoming blueish. In the capillaries of the most active organs—liver and kidney— the reduction from the blue to the colourless condition is so complete that anyone slicing up these organs for the first time invariably says: ' The injection mass has not entered here.' One is often only con- vinced that it has entered and is still in the organ, on the slices being exposed to the air or irrigated with h,,, when, as one watches the cut surface, the streaks of injected vessels emerge into visibility like letters developing in ' sympathetic ' ink. Seen for the first time, this is very striking—more so, we think, than the corresponding methylene blue revival. One of the most convincing demonstrations of the reducing power of the tissues as exerted on soluble Prussian blue was carried out in the isolated kidney of the pig which was actually induced to excrete an artificial, gelatinous, colourless ' urine.' A pig's kidney, an hour or two after the death of the animal, was first of all washed out with 75% saline at 42°C., so that all traces of blood were removed, and colourless saline was running from the renal vein and from the. P
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Keywords: ., bookcentury1900, bookdecade1900, booksubjectbiochem, bookyear1906
