. Endocrinology. (39 cm.). The circumference at thenavel was 25 in. ( cm.) ; at the hips, midway between trochan-ters, 29% in. (74 cm.); at the middle of the thigh, 13% in. () ; and of the leg, 10 in. ( cm.). There was complete absenceof secondary sex characters, very slight lanugo on the mons veneris,absolutely no hair in the axillae or on the face. The breasts were not ?Koportcfl in full in Mcfl. flin. N. St. niimlicr. 1020 557 developed. The face was typically infantile. The hairline was ratherlow, the eyebrows very thin; the nose was slightly retrousse;


. Endocrinology. (39 cm.). The circumference at thenavel was 25 in. ( cm.) ; at the hips, midway between trochan-ters, 29% in. (74 cm.); at the middle of the thigh, 13% in. () ; and of the leg, 10 in. ( cm.). There was complete absenceof secondary sex characters, very slight lanugo on the mons veneris,absolutely no hair in the axillae or on the face. The breasts were not ?Koportcfl in full in Mcfl. flin. N. St. niimlicr. 1020 557 developed. The face was typically infantile. The hairline was ratherlow, the eyebrows very thin; the nose was slightly retrousse; noadiposity was present. The pulse was slow, but otherwise normal;the blood pressure was 124/90. The profile showed slight recessionof the chin; the mouth showed recession of the lower jaw, with poorocculsion of the anterior teeth; the iijjper incisors were very large,lateral canines very small; all permanent teeth were present exceptthe posterior molars. Both lobes and isthmus of the thyroid wereslightly Fig. 1. (A) Note the infantile, virgin type of breast development. I P. iCase 1. age 19. Note the general infantilism, fecies, and underdevelopment ofthe osseous system compared with the normal girl of corresponding age. (C)Infantile vulva ; absence of secondary sex characters. The m-ine was negative, except for a slight trace of blood, including Wasserniann test, was normal. Carbohydratetolerance was increased; blood sugar the first hour tested ;the second hour, The basal metabolistn was 558 IIV1()PIIYSP:AL disokders Radioscopy showed a normal sella turcica, and epiphyseal linesclearly evident in the head of the radius and in all metacarpals andphalanges. Complete ossification had taken place in carpal bones;the phalanges were free from tufting or mushrooming; the boneswere slender. The above ease is believed to eorresimiul to the Loraiii-Levitype of hypopituitarism, and. aecordin^ to our a pure anterior lobe


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Keywords: ., bookcentury1900, bookdecade1910, booksubjectendocrinology, bookye