. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. R48 Annual Report obtained in this laboratory, improved forms of bioluminescent probes are designed and produced for the measurements of intracellular free calcium and superoxide anion. Staff Shimomura, Osamu, Senior Scientist, MBL, and Boston University School of Medicine Shimomura, Akemi. Research Assistant Laboratory of Robert B. Silver This laboratory studies how living cells make decisions. The focus of the research, typically using marine models, is on two main areas: the role of calcium in the regulation of mitotic ce
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. R48 Annual Report obtained in this laboratory, improved forms of bioluminescent probes are designed and produced for the measurements of intracellular free calcium and superoxide anion. Staff Shimomura, Osamu, Senior Scientist, MBL, and Boston University School of Medicine Shimomura, Akemi. Research Assistant Laboratory of Robert B. Silver This laboratory studies how living cells make decisions. The focus of the research, typically using marine models, is on two main areas: the role of calcium in the regulation of mitotic cell division (sea urchins, sand dollars, etc.) and structure/function relationships of hair cell stereociliary movements in vestibular physiology (oyster, toadlish). Other related areas of study, . synaptic transmission (squid), are also pursued. Tools include video light microscopy, multispectral and very high speed (sub-millisecond frame rate) photon counting video light microscopy, telemanipulation of living cells and tissues, and modeling of decision processes. A cornerstone of the laboratory's analytical efforts is high performance computational processing and analysis of video light microscopy images. With luminescent, fluorescent, and absorptive probes both empirical observation and computational modeling of cellular, biochemical and biophysical processes permit interpretation and mapping of space-time patterns of intracellular chemical reactions and calcium signalling in living cells. A variety of//; \iiro biochemical, biophysical, and immunological methods are used. In addition to fundamental biological studies, the stall designs and fabricates optical hardware, and designs software for large video image data processing, analysis, and modeling. Staff Silver, Robert, Associate Scientist Crossin, Glenn, Laboratory Assistant Fripp, William. Research Assistant Hopkins. James, Research Assistant Knudson. Robert, Instrument Engineer Maccaro, Jackie. Laboratory Assistant S
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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology
