Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . thod. It canalso be tinged by aqueous solutionsof gentian-violet, Bismarck brown,or fuchsin. Pathogenesis.—The parasite is always demonstrable in some stageof relapsing fever; with the advancing pyrexia the organisms increase,and disappear during defervescence. The disease may be transmittedto man and monkeys by inoculation with the infected blood. Whendeath has resulted from relapsing fever, the skin commonly shows acharacteristic yellowish hue. Various changes—fatty and granular—hav
Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . thod. It canalso be tinged by aqueous solutionsof gentian-violet, Bismarck brown,or fuchsin. Pathogenesis.—The parasite is always demonstrable in some stageof relapsing fever; with the advancing pyrexia the organisms increase,and disappear during defervescence. The disease may be transmittedto man and monkeys by inoculation with the infected blood. Whendeath has resulted from relapsing fever, the skin commonly shows acharacteristic yellowish hue. Various changes—fatty and granular—have been described in the heart; the spleen is enlarged and softened,the follicles swollen, and the pulp darker than normal. The liver maybe enlarged, the cells fatty and granular, and in some cases^ round-cell infiltration in the neighi)orhood of the portal vein occurs. Granularand fatty changes, sometimes with hemorrhages, are found in the some cases the interstitial tissue is infiltrated, but the change is notcharacteristic. Ulcero-raembranous stomatitis or angina, also called diphtheroid. Fic. 96.—Spirillum of and the Fusi-form Baollus; Othkr Organisms are alsoPresent.—(From case rtporltd by Or. Rostn- bfrgfr.) 174 GENERAL PATHOLOGY. angina and angina of Vincent/ is a disease affecting particularly thetonsils and uvula, less commonly the oral and pharyngeal mucosaor lips; it is characterized by the formation of a superficial membrane,and, in marked cases, necrosis extending into the submucosa. In severeinfection parts of the uvula may be destroyed. The membrane is vellow,or greenish-yellow, and when detached leaves a bleeding or eroded sur-face; glandular enlargement is variable. The actively motile spiro-chasta varies in length from lo // to 30 //, and, like the organism found inrelapsing fever, is extremely tenuous and never stains with the sameintensity as the symbiotic bacillus. The spirillum is usually associatedwith a fusiform rod-shaped or
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