A text book of physiology . f aguinea-pig, the ductus choledochus being ligatured, the fluid mayrise in the manometer to about 200 mm. (equivalent to about 16 1 Phil. Tram. Edin., xxvi. (1870). 2 Jourri. Aiiat. Phys., x. xi. (1876, 77); Brit. Med. J., 1878, 1879. 250 SECRETION OF PANCREATIC JUICE. [Book il mm. mercury), but not much beyond. If water be poured into theopen end of the manometer so as to raise the pressure much above200 mm., resorption into the circulation takes place, and the fluid inthe manometer sinks to, or even below, the normal level1. Thequantity secreted in man in the 24
A text book of physiology . f aguinea-pig, the ductus choledochus being ligatured, the fluid mayrise in the manometer to about 200 mm. (equivalent to about 16 1 Phil. Tram. Edin., xxvi. (1870). 2 Jourri. Aiiat. Phys., x. xi. (1876, 77); Brit. Med. J., 1878, 1879. 250 SECRETION OF PANCREATIC JUICE. [Book il mm. mercury), but not much beyond. If water be poured into theopen end of the manometer so as to raise the pressure much above200 mm., resorption into the circulation takes place, and the fluid inthe manometer sinks to, or even below, the normal level1. Thequantity secreted in man in the 24 hours has been estimatedroughly at about 10 kilos, but the calculations are based on veryimperfect data. Pancreatic juice. The relation of the nervous system to thesecretion of the pancreatic juice has been studied rather more 0. Bernstein2 finds that in the dog the secretion, after food hasbeen taken, follows the curve given in Fig. 42. There is a suddenmaximum rise immediately after food has been taken. This must. Fig. 42. Diagram illustrating the influence of Food on the Secretion ofPancreatic Juice. (N. O. Bernstein.) The abscissa? represent hours after taking food; the ordinates represent in amount of secretion in 10 min. A marked rise is seen at B immediately after foodwas taken, with a secondary rise between the 4th and 5th hours afterwards. Wherethe line is dotted the observation was interrupted. On food being again given at C,another rise is seen, followed in turn by a depression and a secondary rise at the 4thhour. A very similar curve would represent the secretion of bile. be due to nervous action. Then follows a fall, after which there is,as in bile, a secondary rise, the causation of which may, or may not,be nervous in nature. The quantity secreted in 24 hours by manhas been calculated at 300 Like the salivary glands, thepancreas while secreting is flushed, through dilation of its blood-vessels. 1 Friedbinder u. Barisch (Heidenhain), Du Bois-B
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