. Hydroxylamine : its quantitative determination and some double salts . e methyl alcohol and ether. Then a 75^ solution yields di-hydroxy-guanidine hydro-bromide ,C(NH),HBr. The action probably takes place as follows:- CNBr + NH^OH = + HBr + NHgOH,HBr = ,C(:NH) The crystals are colorless flat hygroscopic needles, ±Cinsa and Luzzatto made experiments on the toxicityof hydroxylamine, the influence of its presence on the oxidationproducts in the urine of animala to which hydroxylamlne had beenadministered, Tl^e blood was examined spectroscopically. As apo
. Hydroxylamine : its quantitative determination and some double salts . e methyl alcohol and ether. Then a 75^ solution yields di-hydroxy-guanidine hydro-bromide ,C(NH),HBr. The action probably takes place as follows:- CNBr + NH^OH = + HBr + NHgOH,HBr = ,C(:NH) The crystals are colorless flat hygroscopic needles, ±Cinsa and Luzzatto made experiments on the toxicityof hydroxylamine, the influence of its presence on the oxidationproducts in the urine of animala to which hydroxylamlne had beenadministered, Tl^e blood was examined spectroscopically. As apoison hydroxylamlne is four or five times as powerful as nitrousacid. In the blood the hydroxylamlne is oxidized first to nitrousacid, then reduced to nitric oxide. The most probable interrcddiateaction is the formation of di-hydroxyl ^NHCOlUg •»N(0K)2 orNHgOH-^NO-^HNOg and IIKO+HNO =SNO+H^O The blood spectrum indicates the presence of a nitric oxide compound of haemogeobin together with methaemoglobin. +Ber. 38, 1445-61 ±J, of Ghem, Soc, Ab. 94, 876. -5- Qutmtitativp Deterralnatlone +The met2:iod of Moyelfrigh in which Uie hydroxylamlnowas determined by titration with free iodine in presence of sodiumphosphate and .Magnesium 05clde(Mg 0)was tried. The oxidation reac-tion is quantitative only when one is careful to neutralize the hy-driodic acid formed. Potassium carbonate is not alkaline enough tocompletely neutralize the acid but either sodium phosphate or mag-nesium oxide work well. To the hydroxylamine solution, add suffi-cient amount of sodium phosphate and a slight excess of iodine solu-tion and titrate back with sodium thiosulphate. If the amounts ofhydroxylamine and used iodine are figured from atomic weights, onemolecule of hydroxylamine salt requires two atoms of iodine. It fol-lows that one molecule of hydroxylamine is oxidized by two atoms ofiodine if the hydriodic acid formed is neutralized at once,2NH^0H+SIg=Np0+Hg0+4HI and proves accurately this
Size: 1324px × 1886px
Photo credit: © Reading Room 2020 / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookcentury1900, bookdecade1900, bookidhydroxy, booksubjecttheses
