Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . /. to 2 , thick ; onemargin of the parasite isoutlined by an undulatingmembrane, along the freemargin of which is at-tached a flagellum arising from the centrosome posteriorly and i)rojectingas a free lash from the anterior end of the parasite (see Fig. gg. p. 184).The disease is inoculated by a tsetse-fly—the Glossina palpalis—and hasbeen communicated to a number of mammalia. In man the organismappears to remain as a blood parasite for a considerable length of time,eventually enterin
Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . /. to 2 , thick ; onemargin of the parasite isoutlined by an undulatingmembrane, along the freemargin of which is at-tached a flagellum arising from the centrosome posteriorly and i)rojectingas a free lash from the anterior end of the parasite (see Fig. gg. p. 184).The disease is inoculated by a tsetse-fly—the Glossina palpalis—and hasbeen communicated to a number of mammalia. In man the organismappears to remain as a blood parasite for a considerable length of time,eventually entering the cerebrospinal fluid and giving rise to a fataldisease called sleeping sickness (African lethargy). Laveran and Mcsnil. Trypanosomes et Trjpanosoniiases. IAn enormous amount of literature has recently accumulated cnnav-parasites. The interested reader will fmd the most important articfiles of the Jour, of Tropical Med., Brit. Med. The Rports of the Sleeping Sickness Commission. Ccntralhl. f. i- ? ? -• ?.and xxvi. Annales dc ITnst. Pasteur. and •Bulletin de Ilnst. Fig. qS.— Trypam-ma i \ and Mcsnil stain, ij homo, im., i in. oc. i84 GENERAL PATHOLOGY. Morbid Anatomy.—In the earlier stages there may be no noteworthyalterations; neuralgias, edemas, skin eruptions, enlargement of thelymph-nodes, and emaciation with irregular fever may be present. Afterthe affection attacks the central nervous system Mott has shown thata meningo-encephalitis results. Frequently terminal infection by astreptococcus (hypnococcus of Castellani) produces a definite meningitisfound at autopsy. The possible relation of these organisms to the spirochaetae has beenmentioned on page 172. Coccidiosis is a condition produced by invasion of cells—mostlyepithelium—by parasites called coccidia. They are particularly proneto infect the biliary passages; coccidial cysts of the liver are frequent insome of the lower animals, especially the rabbit, and are o
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