Ketamine drug binding to ion channel, molecular model. Several molecules of the drug ketamine binding to a pentameric ligand-gated ion channel (pLGIC)


Ketamine drug binding to ion channel, molecular model. Several molecules of the drug ketamine binding to a pentameric ligand-gated ion channel (pLGIC). Ketamine is used for inducing and maintaining general anaesthesia. The ketamine molecules are the smaller units (including colour-coded spherical atoms) binding to the large receptor protein forming the shape of a channel (centre). The anaesthetic molecules bind to the extracellular interface between the receptor's five monomers. There are five ketamine molecules per receptor. This model shows the receptor secondary structure (blue ribbons) and electron density map.


Size: 3648px × 4864px
Photo credit: © RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY / Alamy / Afripics
License: Licensed
Model Released: No

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