AMAarchives of neurology & psychiatry . e matter; b, multilocular cyst inright frontal pole formed by dilatation of perivascular lymphatic spaces; c, tumorat head of caudate nucleus pressing into foramen of Munro; d, dilated posteriorhorn of lateral ventricle; note the area of microgyria in left occipital lobe. FREEM AX—TUBEROUS SCLEROSIS 619 cortex was narrow, white and hard, and the white matter was soft and porousexcept where the fibers of the optic radiation ran, skirting the horn of theventricle. This tract was narrow, but apparently in good condition. In the right parietal lobe over an a
AMAarchives of neurology & psychiatry . e matter; b, multilocular cyst inright frontal pole formed by dilatation of perivascular lymphatic spaces; c, tumorat head of caudate nucleus pressing into foramen of Munro; d, dilated posteriorhorn of lateral ventricle; note the area of microgyria in left occipital lobe. FREEM AX—TUBEROUS SCLEROSIS 619 cortex was narrow, white and hard, and the white matter was soft and porousexcept where the fibers of the optic radiation ran, skirting the horn of theventricle. This tract was narrow, but apparently in good condition. In the right parietal lobe over an area 3 by 4 cm. there were numerousabnormally small and branched convolutions, in which scarcely any whitematter could be seen underlying the narrow cortex. The area was notdepressed below the general level as is usual in microgyria. While theseconvolutions were of normal consistence and relatively normal architecture,there was a sharply defined area of sclerosis immediately adjacent. A similararea appeared in the left occipital Fig. 2.—Hypertrophic convolution, broadened and umbilicate at surface, dueto neuroglial overgrowth. The gliosis diminishes at the bottom of the acid-hematin stain: a. patch of beginning sclerosis. At the head of the caudate nucleus on the right there was a tumor measuring18 by 10 mm. pressing down into the foramen of Monro (Fig. 1). The tumorsprang superficially from the caudate nucleus, was of soft consistence, ratherfriable and darker than the surrounding tissue. It was circumscribed thoughnot encapsulated. Its surface in the ventricle was fungoid and irregular, butat the sides it was smoother and apparently covered by ependyma. It did notinvade the nervous tissue. At other points on the surface of the caudatenucleus on both sides there were smaller tumors varying from 2 to 6 mm. indiameter. In the third ventricle there were tumors up to 5 mm. in diameter,especially along the striae terminales. These smaller tumors oc
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Keywords: ., bookcentury1900, bookdecade1910, bookpublisherchica, bookyear1919
